Fragments and Focused Sets

Fragment Libraries

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🧩 Fragment 5K screening set 10 - 200mM

5 000 fragments of concentrations between 10 – 200 mM, designed by Flavio Ballante (CBCS)

🧩 KeyOrganics Flour Fragment 100-200mM DMSO-d6

462 fragments 200mM available, suitable for NMR screening.

🧩 SLL CIMS Fragment Library 50mM

1 000 fragments 50mM availble, designed by Anna-Lena Gustavsson (CBCS), Evert Homan (T. Helleday group), Peter Brandt (Kdex)

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Focused Sets

🎯 Enamine Molecular Glue Set

4 500 compounds available
Designed to capture the widest possible range of novel chemotypes of CRBN binders, Molecular Glues can induce proximity between a target protein and an E3 ubiquitin ligase, resulting in selective degradation of the target protein. The potential of targeted protein degradation, opening new avenues in drug discovery—particularly for proteins previously considered “undruggable.” this library is designed to engage multiple E3 ligases.

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🎯 CBCS Steroids Set (Sjövall)

177 compounds available
Donated steriod cpds

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🎯 MCE Epigenetics

769 compounds available
Includes any process that alters gene activity without changing the DNA sequence and can be transmitted to daughter cells.

🎯 MCE Nucleotides

177 compounds available

🎯 Selleck KKI

378 compounds available
A set of known kinase inhibitors

🎯 SGC Bromodomain Probes

40 compounds available
Epigenetic chemical probes

🎯 SPECS Jump Set

395 compounds available
Target and MoA. Designed by Broad Institute. Suits cellular imaging, image analysis and high dimensional data analytics.
Read more: Information about jump-cellpainting from Broad

🎯 Otava Nucleobase Derivatives

958 compounds available
NIH compounds, nucleobase derivatives

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